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Mechanisms of Body Weight Reduction by Black Tea Polyphenols

Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea,...

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Detalles Bibliográficos
Autores principales: Pan, Haibo, Gao, Ying, Tu, Youying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273558/
https://www.ncbi.nlm.nih.gov/pubmed/27941615
http://dx.doi.org/10.3390/molecules21121659
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author Pan, Haibo
Gao, Ying
Tu, Youying
author_facet Pan, Haibo
Gao, Ying
Tu, Youying
author_sort Pan, Haibo
collection PubMed
description Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as “fermented tea”, has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols. Black tea polyphenols exert a positive effect on inhibiting obesity involving in two major mechanisms: (i) inhibiting lipid and saccharide digestion, absorption and intake, thus reducing calorie intake; and (ii) promoting lipid metabolism by activating AMP-activated protein kinase to attenuate lipogenesis and enhance lipolysis, and decreasing lipid accumulation by inhibiting the differentiation and proliferation of preadipocytes; (iii) blocking the pathological processes of obesity and comorbidities of obesity by reducing oxidative stress. Epidemiological studies of the health relevance between anti-obesity and black tea polyphenols consumption remain to be further investigated.
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spelling pubmed-62735582018-12-28 Mechanisms of Body Weight Reduction by Black Tea Polyphenols Pan, Haibo Gao, Ying Tu, Youying Molecules Review Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as “fermented tea”, has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols. Black tea polyphenols exert a positive effect on inhibiting obesity involving in two major mechanisms: (i) inhibiting lipid and saccharide digestion, absorption and intake, thus reducing calorie intake; and (ii) promoting lipid metabolism by activating AMP-activated protein kinase to attenuate lipogenesis and enhance lipolysis, and decreasing lipid accumulation by inhibiting the differentiation and proliferation of preadipocytes; (iii) blocking the pathological processes of obesity and comorbidities of obesity by reducing oxidative stress. Epidemiological studies of the health relevance between anti-obesity and black tea polyphenols consumption remain to be further investigated. MDPI 2016-12-07 /pmc/articles/PMC6273558/ /pubmed/27941615 http://dx.doi.org/10.3390/molecules21121659 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Pan, Haibo
Gao, Ying
Tu, Youying
Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title_full Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title_fullStr Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title_full_unstemmed Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title_short Mechanisms of Body Weight Reduction by Black Tea Polyphenols
title_sort mechanisms of body weight reduction by black tea polyphenols
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273558/
https://www.ncbi.nlm.nih.gov/pubmed/27941615
http://dx.doi.org/10.3390/molecules21121659
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