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Mechanisms of Body Weight Reduction by Black Tea Polyphenols
Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273558/ https://www.ncbi.nlm.nih.gov/pubmed/27941615 http://dx.doi.org/10.3390/molecules21121659 |
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author | Pan, Haibo Gao, Ying Tu, Youying |
author_facet | Pan, Haibo Gao, Ying Tu, Youying |
author_sort | Pan, Haibo |
collection | PubMed |
description | Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as “fermented tea”, has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols. Black tea polyphenols exert a positive effect on inhibiting obesity involving in two major mechanisms: (i) inhibiting lipid and saccharide digestion, absorption and intake, thus reducing calorie intake; and (ii) promoting lipid metabolism by activating AMP-activated protein kinase to attenuate lipogenesis and enhance lipolysis, and decreasing lipid accumulation by inhibiting the differentiation and proliferation of preadipocytes; (iii) blocking the pathological processes of obesity and comorbidities of obesity by reducing oxidative stress. Epidemiological studies of the health relevance between anti-obesity and black tea polyphenols consumption remain to be further investigated. |
format | Online Article Text |
id | pubmed-6273558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62735582018-12-28 Mechanisms of Body Weight Reduction by Black Tea Polyphenols Pan, Haibo Gao, Ying Tu, Youying Molecules Review Obesity is one of the most common nutritional diseases worldwide. This disease causes health problems, such as dyslipidemia, hyperglycemia, hypertension and inflammation. There are drugs used to inhibit obesity. However, they have serious side effects outweighing their beneficial effects. Black tea, commonly referred to as “fermented tea”, has shown a positive effect on reducing body weight in animal models. Black tea polyphenols are the major components in black tea which reduce body weight. Black tea polyphenols are more effective than green tea polyphenols. Black tea polyphenols exert a positive effect on inhibiting obesity involving in two major mechanisms: (i) inhibiting lipid and saccharide digestion, absorption and intake, thus reducing calorie intake; and (ii) promoting lipid metabolism by activating AMP-activated protein kinase to attenuate lipogenesis and enhance lipolysis, and decreasing lipid accumulation by inhibiting the differentiation and proliferation of preadipocytes; (iii) blocking the pathological processes of obesity and comorbidities of obesity by reducing oxidative stress. Epidemiological studies of the health relevance between anti-obesity and black tea polyphenols consumption remain to be further investigated. MDPI 2016-12-07 /pmc/articles/PMC6273558/ /pubmed/27941615 http://dx.doi.org/10.3390/molecules21121659 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Pan, Haibo Gao, Ying Tu, Youying Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title | Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title_full | Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title_fullStr | Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title_full_unstemmed | Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title_short | Mechanisms of Body Weight Reduction by Black Tea Polyphenols |
title_sort | mechanisms of body weight reduction by black tea polyphenols |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273558/ https://www.ncbi.nlm.nih.gov/pubmed/27941615 http://dx.doi.org/10.3390/molecules21121659 |
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