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Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway
Trans-fatty acid consumption has been reported as a risk factor for metabolic disorders and targeted organ damages. Nonetheless, little is known about the roles and mechanisms of trans-fatty acids in obesity, insulin resistance (IR) and hepatic steatosis. Adult C57BL/6 male mice were fed with four d...
Autores principales: | Zhao, Xiaona, Shen, Cheng, Zhu, Hong, Wang, Cong, Liu, Xiangwei, Sun, Xiaolei, Han, Shasha, Wang, Peng, Dong, Zhen, Ma, Xin, Hu, Kai, Sun, Aijun, Ge, Junbo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273562/ https://www.ncbi.nlm.nih.gov/pubmed/27248994 http://dx.doi.org/10.3390/molecules21060705 |
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