Solubilization Behavior of Polyene Antibiotics in Nanomicellar System: Insights from Molecular Dynamics Simulation of the Amphotericin B and Nystatin Interactions with Polysorbate 80

Amphotericin B (AmB) and Nystatin (Nys) are the drugs of choice for treatment of systemic and superficial mycotic infections, respectively, with their full clinical potential unrealized due to the lack of high therapeutic index formulations for their solubilized delivery. In the present study, using...

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Detalles Bibliográficos
Autores principales: Mobasheri, Meysam, Attar, Hossein, Rezayat Sorkhabadi, Seyed Mehdi, Khamesipour, Ali, Jaafari, Mahmoud Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273564/
https://www.ncbi.nlm.nih.gov/pubmed/26712721
http://dx.doi.org/10.3390/molecules21010006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273564/
https://www.ncbi.nlm.nih.gov/pubmed/26712721
http://dx.doi.org/10.3390/molecules21010006

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