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Synthesis and Pharmacological Evaluation of New 3,4-Dihydroisoquinolin Derivatives Containing Heterocycle as Potential Anticonvulsant Agents

Two novel series of 3,4-dihydroisoquinolin with heterocycle derivatives (4a–t and 9a–e) were synthesized and evaluated for their anticonvulsant activity using maximal electroshock (MES) test and pentylenetetrazole (PTZ)-induced seizure test. All compounds were characterized by IR, (1)H-NMR, (13)C-NM...

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Detalles Bibliográficos
Autores principales:	Zhang, Hong-Jian, Shen, Qing-Kun, Jin, Chun-Mei, Quan, Zhe-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273582/ https://www.ncbi.nlm.nih.gov/pubmed/27916842 http://dx.doi.org/10.3390/molecules21121635

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