Synthesis and Pharmacological Evaluation of New 3,4-Dihydroisoquinolin Derivatives Containing Heterocycle as Potential Anticonvulsant Agents

Two novel series of 3,4-dihydroisoquinolin with heterocycle derivatives (4a–t and 9a–e) were synthesized and evaluated for their anticonvulsant activity using maximal electroshock (MES) test and pentylenetetrazole (PTZ)-induced seizure test. All compounds were characterized by IR, (1)H-NMR, (13)C-NM...

ver descrição completa

Detalhes bibliográficos
Principais autores: Zhang, Hong-Jian, Shen, Qing-Kun, Jin, Chun-Mei, Quan, Zhe-Shan
Formato: Online Atigo Texto
Idioma:English
Publicado em: MDPI 2016
Assuntos:
Article
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273582/
https://www.ncbi.nlm.nih.gov/pubmed/27916842
http://dx.doi.org/10.3390/molecules21121635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273582/
https://www.ncbi.nlm.nih.gov/pubmed/27916842
http://dx.doi.org/10.3390/molecules21121635

Registros relacionados