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Metabolic Responses of Bacterial Cells to Immobilization
In recent years immobilized cells have commonly been used for various biotechnological applications, e.g., antibiotic production, soil bioremediation, biodegradation and biotransformation of xenobiotics in wastewater treatment plants. Although the literature data on the physiological changes and beh...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273605/ https://www.ncbi.nlm.nih.gov/pubmed/27455220 http://dx.doi.org/10.3390/molecules21070958 |
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author | Żur, Joanna Wojcieszyńska, Danuta Guzik, Urszula |
author_facet | Żur, Joanna Wojcieszyńska, Danuta Guzik, Urszula |
author_sort | Żur, Joanna |
collection | PubMed |
description | In recent years immobilized cells have commonly been used for various biotechnological applications, e.g., antibiotic production, soil bioremediation, biodegradation and biotransformation of xenobiotics in wastewater treatment plants. Although the literature data on the physiological changes and behaviour of cells in the immobilized state remain fragmentary, it is well documented that in natural settings microorganisms are mainly found in association with surfaces, which results in biofilm formation. Biofilms are characterized by genetic and physiological heterogeneity and the occurrence of altered microenvironments within the matrix. Microbial cells in communities display a variety of metabolic differences as compared to their free-living counterparts. Immobilization of bacteria can occur either as a natural phenomenon or as an artificial process. The majority of changes observed in immobilized cells result from protection provided by the supports. Knowledge about the main physiological responses occurring in immobilized cells may contribute to improving the efficiency of immobilization techniques. This paper reviews the main metabolic changes exhibited by immobilized bacterial cells, including growth rate, biodegradation capabilities, biocatalytic efficiency and plasmid stability. |
format | Online Article Text |
id | pubmed-6273605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62736052018-12-28 Metabolic Responses of Bacterial Cells to Immobilization Żur, Joanna Wojcieszyńska, Danuta Guzik, Urszula Molecules Review In recent years immobilized cells have commonly been used for various biotechnological applications, e.g., antibiotic production, soil bioremediation, biodegradation and biotransformation of xenobiotics in wastewater treatment plants. Although the literature data on the physiological changes and behaviour of cells in the immobilized state remain fragmentary, it is well documented that in natural settings microorganisms are mainly found in association with surfaces, which results in biofilm formation. Biofilms are characterized by genetic and physiological heterogeneity and the occurrence of altered microenvironments within the matrix. Microbial cells in communities display a variety of metabolic differences as compared to their free-living counterparts. Immobilization of bacteria can occur either as a natural phenomenon or as an artificial process. The majority of changes observed in immobilized cells result from protection provided by the supports. Knowledge about the main physiological responses occurring in immobilized cells may contribute to improving the efficiency of immobilization techniques. This paper reviews the main metabolic changes exhibited by immobilized bacterial cells, including growth rate, biodegradation capabilities, biocatalytic efficiency and plasmid stability. MDPI 2016-07-22 /pmc/articles/PMC6273605/ /pubmed/27455220 http://dx.doi.org/10.3390/molecules21070958 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Żur, Joanna Wojcieszyńska, Danuta Guzik, Urszula Metabolic Responses of Bacterial Cells to Immobilization |
title | Metabolic Responses of Bacterial Cells to Immobilization |
title_full | Metabolic Responses of Bacterial Cells to Immobilization |
title_fullStr | Metabolic Responses of Bacterial Cells to Immobilization |
title_full_unstemmed | Metabolic Responses of Bacterial Cells to Immobilization |
title_short | Metabolic Responses of Bacterial Cells to Immobilization |
title_sort | metabolic responses of bacterial cells to immobilization |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273605/ https://www.ncbi.nlm.nih.gov/pubmed/27455220 http://dx.doi.org/10.3390/molecules21070958 |
work_keys_str_mv | AT zurjoanna metabolicresponsesofbacterialcellstoimmobilization AT wojcieszynskadanuta metabolicresponsesofbacterialcellstoimmobilization AT guzikurszula metabolicresponsesofbacterialcellstoimmobilization |