Synthesis and the Biological Activity of Phosphonylated 1,2,3-Triazolenaphthalimide Conjugates

A novel series of diethyl {4-[(5-substituted-1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-methyl]-1H-1,2,3-triazol-1-yl}alkylphosphonates designed as analogues of amonafide was synthesized. All phosphonates were assessed for antiviral activity against a broad range of DNA and RNA viruses and several...

Descripción completa

Detalles Bibliográficos
Autores principales: Głowacka, Iwona E., Gulej, Rafał, Grzonkowski, Piotr, Andrei, Graciela, Schols, Dominique, Snoeck, Robert, Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273621/
https://www.ncbi.nlm.nih.gov/pubmed/27792200
http://dx.doi.org/10.3390/molecules21111420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273621/
https://www.ncbi.nlm.nih.gov/pubmed/27792200
http://dx.doi.org/10.3390/molecules21111420

Ejemplares similares