Design, Synthesis and Biological Evaluation of Novel Primaquine-Cinnamic Acid Conjugates of the Amide and Acylsemicarbazide Type

In this paper design and synthesis of a scaffold comprising primaquine (PQ) motif and cinnamic acid derivatives (CADs) bound directly (compounds 3a–k) or via a spacer (compounds 7a–k) are reported. In the first series of compounds, PQ and various CADs were connected by amide bonds and in the second...

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Detalles Bibliográficos
Autores principales: Pavić, Kristina, Perković, Ivana, Gilja, Petra, Kozlina, Filip, Ester, Katja, Kralj, Marijeta, Schols, Dominique, Hadjipavlou-Litina, Dimitra, Pontiki, Eleni, Zorc, Branka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273687/
https://www.ncbi.nlm.nih.gov/pubmed/27916811
http://dx.doi.org/10.3390/molecules21121629

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