Synthesis and Evaluation of Novel α-Aminoamides Containing an Indole Moiety for the Treatment of Neuropathic Pain

The α-aminoamide family of sodium ion channel blockers have exhibited analgesic effects on neuropathic pain. Here, a series of novel α-aminoamides containing an indole ring were designed and synthesized. These compounds were evaluated in mice using a formalin test and they exhibited significant anti...

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Detalles Bibliográficos
Autores principales: Li, Haotian, Fan, Shiyong, Cheng, Jingchao, Zhang, Ping, Zhong, Bohua, Shi, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273711/
https://www.ncbi.nlm.nih.gov/pubmed/27347907
http://dx.doi.org/10.3390/molecules21070793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273711/
https://www.ncbi.nlm.nih.gov/pubmed/27347907
http://dx.doi.org/10.3390/molecules21070793

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