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Synthesis and Evaluation of New Benzodioxole- Based Thiosemicarbazone Derivatives as Potential Antitumor Agents

New benzodioxole-based thiosemicarbazone derivatives were synthesized and evaluated for their cytotoxic effects on A549 human lung adenocarcinoma, C6 rat glioma and NIH/3T3 mouse embryonic fibroblast cells. In order to examine the correlation between anticancer activity and cholinesterases, the comp...

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Detalles Bibliográficos
Autores principales: Altıntop, Mehlika Dilek, Temel, Halide Edip, Sever, Belgin, Akalın Çiftçi, Gülşen, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273715/
https://www.ncbi.nlm.nih.gov/pubmed/27879683
http://dx.doi.org/10.3390/molecules21111598