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Molecular Mechanism of the Flavonoid Natural Product Dryocrassin ABBA against Staphylococcus aureus Sortase A

The intractability of bacterial resistance presents a dilemma for therapies against Staphylococcus aureus (S. aureus) infection. Effective anti-virulence strategies are urgently needed, reflecting the proliferation of resistant strains. Inhibitors of sortase A (SrtA), enzymes that anchor virulence-r...

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Detalles Bibliográficos
Autores principales: Zhang, Bing, Wang, Xiyan, Wang, Lin, Chen, Shuiye, Shi, Dongxue, Wang, Hongsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273746/
https://www.ncbi.nlm.nih.gov/pubmed/27792196
http://dx.doi.org/10.3390/molecules21111428