The Synthesis of the Metabolites of 2′,3′,5′-Tri-O-acetyl-N(6)-(3-hydroxyphenyl) Adenosine (WS070117)

Seven metabolites of 2′,3′,5′-tri-O-acetyl-N(6)-(3-hydroxyphenyl) adenosine (WS070117) were synthesized by deacetylation, hydrolysis, cyclization, sulfonylation and glycosylation reactions, respectively. All these compounds, which could be useful as material standards for metabolic research, were ch...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Xuan, Wu, Hong-Na, Li, Bo, Wu, Hong-Lin, Wang, Dong-Mei, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273794/
https://www.ncbi.nlm.nih.gov/pubmed/26729072
http://dx.doi.org/10.3390/molecules21010008
Descripción
Sumario:Seven metabolites of 2′,3′,5′-tri-O-acetyl-N(6)-(3-hydroxyphenyl) adenosine (WS070117) were synthesized by deacetylation, hydrolysis, cyclization, sulfonylation and glycosylation reactions, respectively. All these compounds, which could be useful as material standards for metabolic research, were characterized by NMR and HPLC-MS (ESI) analyses.

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