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Synthesis and Selective Cytotoxic Activities on Rhabdomyosarcoma and Noncancerous Cells of Some Heterocyclic Chalcones

Chemically diverse heterocyclic chalcones were prepared and evaluated for cytotoxicity, aiming to push forward potency and selectivity. They were tested against rhabdomyosarcoma (RMS) and noncancerous cell line (LLC-PK1). The influence of heteroaryl patterns on rings A and B was studied. Heterocycle...

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Detalles Bibliográficos
Autores principales: Do, Tuong-Ha, Nguyen, Dai-Minh, Truong, Van-Dat, Do, Thi-Hong-Tuoi, Le, Minh-Tri, Pham, Thanh-Quan, Thai, Khac-Minh, Tran, Thanh-Dao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273843/
https://www.ncbi.nlm.nih.gov/pubmed/27005608
http://dx.doi.org/10.3390/molecules21030329