Synthesis and Crystal Structures of Benzimidazole-2-thione Derivatives by Alkylation Reactions

Alkylated, benzylated and bromoalkylated benzimidazole-thione that intramolecularly heterocyclized to 3,4-dihydro-2H-[1,3]thiazino[3,2-a]benzimidazole were synthesized. The chemical structure of the synthesized product was characterized by Infra Red, (1)H-NMR, (13)C-NMR, and Mass spectroscopy. Furth...

Descripción completa

Detalles Bibliográficos
Autores principales: El Ashry, El Sayed H., El Kilany, Yeldez, Nahas, Nariman M., Barakat, Assem, Al-Qurashi, Nadia, Ghabbour, Hazem A., Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273855/
https://www.ncbi.nlm.nih.gov/pubmed/26703551
http://dx.doi.org/10.3390/molecules21010012
Descripción
Sumario:Alkylated, benzylated and bromoalkylated benzimidazole-thione that intramolecularly heterocyclized to 3,4-dihydro-2H-[1,3]thiazino[3,2-a]benzimidazole were synthesized. The chemical structure of the synthesized product was characterized by Infra Red, (1)H-NMR, (13)C-NMR, and Mass spectroscopy. Furthermore, the molecular structures of 8 and 9 were confirmed by X-ray single crystallography in different space groups, Pbca and P2(1)/c, respectively.

Ejemplares similares