Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors

Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, na...

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Autores principales: Sivasothy, Yasodha, Krishnan, Thiba, Chan, Kok-Gan, Abdul Wahab, Siti Mariam, Othman, Muhamad Aqmal, Litaudon, Marc, Awang, Khalijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273857/
https://www.ncbi.nlm.nih.gov/pubmed/27102164
http://dx.doi.org/10.3390/molecules21030391
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author Sivasothy, Yasodha
Krishnan, Thiba
Chan, Kok-Gan
Abdul Wahab, Siti Mariam
Othman, Muhamad Aqmal
Litaudon, Marc
Awang, Khalijah
author_facet Sivasothy, Yasodha
Krishnan, Thiba
Chan, Kok-Gan
Abdul Wahab, Siti Mariam
Othman, Muhamad Aqmal
Litaudon, Marc
Awang, Khalijah
author_sort Sivasothy, Yasodha
collection PubMed
description Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, namely Escherichia coli [pSB401] and Escherichia coli [pSB1075], whereby the potential of giganteone A (4) as a suitable anti-quorum sensing agent was demonstrated.
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spelling pubmed-62738572018-12-28 Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors Sivasothy, Yasodha Krishnan, Thiba Chan, Kok-Gan Abdul Wahab, Siti Mariam Othman, Muhamad Aqmal Litaudon, Marc Awang, Khalijah Molecules Communication Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, namely Escherichia coli [pSB401] and Escherichia coli [pSB1075], whereby the potential of giganteone A (4) as a suitable anti-quorum sensing agent was demonstrated. MDPI 2016-03-21 /pmc/articles/PMC6273857/ /pubmed/27102164 http://dx.doi.org/10.3390/molecules21030391 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Sivasothy, Yasodha
Krishnan, Thiba
Chan, Kok-Gan
Abdul Wahab, Siti Mariam
Othman, Muhamad Aqmal
Litaudon, Marc
Awang, Khalijah
Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title_full Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title_fullStr Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title_full_unstemmed Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title_short Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors
title_sort quorum sensing inhibitory activity of giganteone a from myristica cinnamomea king against escherichia coli biosensors
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273857/
https://www.ncbi.nlm.nih.gov/pubmed/27102164
http://dx.doi.org/10.3390/molecules21030391
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