Low-Molecular Weight Polyethylenimine Modified with Pluronic 123 and RGD- or Chimeric RGD-NLS Peptide: Characteristics and Transfection Efficacy of Their Complexes with Plasmid DNA

To solve the problem of transfection efficiency vs. cytotoxicity and tumor-targeting ability when polyethylenimine (PEI) was used as a nonviral gene delivery vector, new degradable PEI polymers were synthesized via cross-linking low-molecular-weight PEI with Pluronic P123 and then further coupled wi...

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Detalles Bibliográficos
Autores principales: Hu, Jing, Zhao, Wenfang, Liu, Kehai, Yu, Qian, Mao, Yuan, Lu, Zeyu, Zhang, Yaguang, Zhu, Manman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273895/
https://www.ncbi.nlm.nih.gov/pubmed/27213305
http://dx.doi.org/10.3390/molecules21050655

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