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Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer

Human peptide deformylase (HsPDF) is an important target for anticancer drug discovery. In view of the limited HsPDF, inhibitors were reported, and high-throughput virtual screening (HTVS) studies based on HsPDF for developing new PDF inhibitors remain to be reported. We reported here on diverse sma...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Wang, Tao, Qiu, Shengzhi, Zhu, Yasheng, Liang, Li, Zheng, Youguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273975/
https://www.ncbi.nlm.nih.gov/pubmed/27023495
http://dx.doi.org/10.3390/molecules21040396