A Versatile Axle for the Construction of Disassemblage Rotaxanes

Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and (1)H-NMR analysis. The axle is highly charged, w...

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Detalles Bibliográficos
Autores principales: Powers, Lucas A., Smithrud, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274001/
https://www.ncbi.nlm.nih.gov/pubmed/27517897
http://dx.doi.org/10.3390/molecules21081043
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author Powers, Lucas A.
Smithrud, David B.
author_facet Powers, Lucas A.
Smithrud, David B.
author_sort Powers, Lucas A.
collection PubMed
description Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and (1)H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors.
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spelling pubmed-62740012018-12-28 A Versatile Axle for the Construction of Disassemblage Rotaxanes Powers, Lucas A. Smithrud, David B. Molecules Article Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and (1)H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors. MDPI 2016-08-10 /pmc/articles/PMC6274001/ /pubmed/27517897 http://dx.doi.org/10.3390/molecules21081043 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Powers, Lucas A.
Smithrud, David B.
A Versatile Axle for the Construction of Disassemblage Rotaxanes
title A Versatile Axle for the Construction of Disassemblage Rotaxanes
title_full A Versatile Axle for the Construction of Disassemblage Rotaxanes
title_fullStr A Versatile Axle for the Construction of Disassemblage Rotaxanes
title_full_unstemmed A Versatile Axle for the Construction of Disassemblage Rotaxanes
title_short A Versatile Axle for the Construction of Disassemblage Rotaxanes
title_sort versatile axle for the construction of disassemblage rotaxanes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274001/
https://www.ncbi.nlm.nih.gov/pubmed/27517897
http://dx.doi.org/10.3390/molecules21081043
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