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Virtual Screening for Potential Allosteric Inhibitors of Cyclin-Dependent Kinase 2 from Traditional Chinese Medicine

Cyclin-dependent kinase 2 (CDK2), a member of Cyclin-dependent kinases (CDKs), plays an important role in cell division and DNA replication. It is regarded as a desired target to treat cancer and tumor by interrupting aberrant cell proliferation. Compared to lower subtype selectivity of CDK2 ATP-com...

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Detalles Bibliográficos
Autores principales:	Lu, Fang, Luo, Ganggang, Qiao, Liansheng, Jiang, Ludi, Li, Gongyu, Zhang, Yanling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274045/ https://www.ncbi.nlm.nih.gov/pubmed/27657032 http://dx.doi.org/10.3390/molecules21091259

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