Azidation in the Difunctionalization of Olefins

Organic azides are key motifs in compounds of relevance to chemical biology, medicinal chemistry and materials science. In addition, they also serve as useful building blocks due to their remarkable reactivity. Therefore, the development of efficient protocols to synthesize these compounds is of gre...

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Detalles Bibliográficos
Autores principales: Wu, Kai, Liang, Yujie, Jiao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274056/
https://www.ncbi.nlm.nih.gov/pubmed/26999085
http://dx.doi.org/10.3390/molecules21030352
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author Wu, Kai
Liang, Yujie
Jiao, Ning
author_facet Wu, Kai
Liang, Yujie
Jiao, Ning
author_sort Wu, Kai
collection PubMed
description Organic azides are key motifs in compounds of relevance to chemical biology, medicinal chemistry and materials science. In addition, they also serve as useful building blocks due to their remarkable reactivity. Therefore, the development of efficient protocols to synthesize these compounds is of great significance. This paper reviews the major applications and development of azidation in difunctionalization of olefins using azide reagents.
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spelling pubmed-62740562018-12-28 Azidation in the Difunctionalization of Olefins Wu, Kai Liang, Yujie Jiao, Ning Molecules Review Organic azides are key motifs in compounds of relevance to chemical biology, medicinal chemistry and materials science. In addition, they also serve as useful building blocks due to their remarkable reactivity. Therefore, the development of efficient protocols to synthesize these compounds is of great significance. This paper reviews the major applications and development of azidation in difunctionalization of olefins using azide reagents. MDPI 2016-03-16 /pmc/articles/PMC6274056/ /pubmed/26999085 http://dx.doi.org/10.3390/molecules21030352 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wu, Kai
Liang, Yujie
Jiao, Ning
Azidation in the Difunctionalization of Olefins
title Azidation in the Difunctionalization of Olefins
title_full Azidation in the Difunctionalization of Olefins
title_fullStr Azidation in the Difunctionalization of Olefins
title_full_unstemmed Azidation in the Difunctionalization of Olefins
title_short Azidation in the Difunctionalization of Olefins
title_sort azidation in the difunctionalization of olefins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274056/
https://www.ncbi.nlm.nih.gov/pubmed/26999085
http://dx.doi.org/10.3390/molecules21030352
work_keys_str_mv AT wukai azidationinthedifunctionalizationofolefins
AT liangyujie azidationinthedifunctionalizationofolefins
AT jiaoning azidationinthedifunctionalizationofolefins

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