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Sulforaphane Analogues with Heterocyclic Moieties: Syntheses and Inhibitory Activities against Cancer Cell Lines

Recent studies have shown that sulforaphane (SFN) selectively inhibits the growth of ALDH(+) breast cancer stem-like cells.Herein, a series of SFN analogues were synthesized and evaluated against breast cancer cell lines MCF-7 and SUM-159, and the leukemia stem cell-like cell line KG-1a. These SFN a...

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Detalles Bibliográficos
Autores principales: Shi, Ye-Hui, Dai, Dong-Fang, Li, Jing, Dong, Yan-Wei, Jiang, Yin, Li, Huan-Gong, Gao, Yuan, Chong, Chuan-Ke, Li, Hui-Ying, Chu, Xiao-Qian, Yang, Cheng, Zhang, Quan, Tong, Zhong-Sheng, Bai, Cui-Gai, Chen, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274066/
https://www.ncbi.nlm.nih.gov/pubmed/27110751
http://dx.doi.org/10.3390/molecules21040514