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Discovery of Uracil Derivatives as Potent Inhibitors of Fatty Acid Amide Hydrolase

Fatty Acid Amide Hydrolase (FAAH) is an intracellular serine enzyme involved in the biological degradation of the fatty acid ethanolamide family of signaling lipids, which exerts neuroprotective, anti-inflammatory, and analgesic properties. In the present study, a conjugated 2,4-dioxo-pyrimidine-1-c...

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Detalles Bibliográficos
Autores principales:	Qiu, Yan, Zhang, Yang, Li, Yuhang, Ren, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274076/ https://www.ncbi.nlm.nih.gov/pubmed/26901181 http://dx.doi.org/10.3390/molecules21020229

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