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Stereoselective Reduction of Imines with Trichlorosilane Using Solid-Supported Chiral Picolinamides
The stereoselective reduction of imines with trichlorosilane catalyzed by chiral Lewis bases is a well-established procedure for the synthesis of enantio-enriched amines. Five supported cinchona-based picolinamides have been prepared and their activity tested in a model reaction. The comparison of d...
Autores principales: | Fernandes, Sílvia D., Porta, Riccardo, Barrulas, Pedro C., Puglisi, Alessandra, Burke, Anthony J., Benaglia, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274114/ https://www.ncbi.nlm.nih.gov/pubmed/27608000 http://dx.doi.org/10.3390/molecules21091182 |
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