Hybrid Molecules Containing a 7-Chloro-4-aminoquinoline Nucleus and a Substituted 2-Pyrazoline with Antiproliferative and Antifungal Activity

Twenty-four new hybrid analogues (15–38) containing 7-chloro-4-aminoquinoline and 2-pyrazoline N-heterocyclic fragments were synthesized. Twelve of the new compounds were evaluated against 58 human cancer cell lines by the U.S. National Cancer Institute (NCI). Compounds 25, 30, 31, 36, and 37 showed...

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Detalles Bibliográficos
Autores principales: Montoya, Alba, Quiroga, Jairo, Abonia, Rodrigo, Derita, Marcos, Sortino, Maximiliano, Ornelas, Alfredo, Zacchino, Susana, Insuasty, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274157/
https://www.ncbi.nlm.nih.gov/pubmed/27472314
http://dx.doi.org/10.3390/molecules21080969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274157/
https://www.ncbi.nlm.nih.gov/pubmed/27472314
http://dx.doi.org/10.3390/molecules21080969

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