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Bryonolic Acid, a Triterpenoid, Protect Against N-methyl-d-Aspartate-Induced Neurotoxicity in PC12 Cells

Calcium overload is considered to be one of the mechanisms of cerebral ischemia. Ca(2+) influx and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and cAMP response element-binding protein (CREB) phosphorylation are considered to be involved in N-Methyl-d-aspartate (NMDA)-induced apoptosis pr...

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Detalles Bibliográficos
Autores principales: Que, Jinhua, Ye, Miao, Zhang, Yuqin, Xu, Wen, Li, Huang, Xu, Wei, Chu, Kedan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274240/
https://www.ncbi.nlm.nih.gov/pubmed/27043504
http://dx.doi.org/10.3390/molecules21040418