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Structural Determinants of Alkyne Reactivity in Copper-Catalyzed Azide-Alkyne Cycloadditions

This work represents our initial effort in identifying azide/alkyne pairs for optimal reactivity in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. In previous works, we have identified chelating azides, in particular 2-picolyl azide, as “privileged” azide substrates with high CuAAC r...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoguang, Liu, Peiye, Zhu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274337/ https://www.ncbi.nlm.nih.gov/pubmed/27941684 http://dx.doi.org/10.3390/molecules21121697

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