Cargando…

Casbane Diterpenes from Red Sea Coral Sinularia polydactyla

The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Hegazy, Mohamed-Elamir F., Mohamed, Tarik A., Elshamy, Abdelsamed I., Al-Hammady, Montaser A., Ohta, Shinji, Paré, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274415/
https://www.ncbi.nlm.nih.gov/pubmed/26950110
http://dx.doi.org/10.3390/molecules21030308
_version_ 1783377612935004160
author Hegazy, Mohamed-Elamir F.
Mohamed, Tarik A.
Elshamy, Abdelsamed I.
Al-Hammady, Montaser A.
Ohta, Shinji
Paré, Paul W.
author_facet Hegazy, Mohamed-Elamir F.
Mohamed, Tarik A.
Elshamy, Abdelsamed I.
Al-Hammady, Montaser A.
Ohta, Shinji
Paré, Paul W.
author_sort Hegazy, Mohamed-Elamir F.
collection PubMed
description The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4–5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis.
format Online
Article
Text
id pubmed-6274415
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62744152018-12-28 Casbane Diterpenes from Red Sea Coral Sinularia polydactyla Hegazy, Mohamed-Elamir F. Mohamed, Tarik A. Elshamy, Abdelsamed I. Al-Hammady, Montaser A. Ohta, Shinji Paré, Paul W. Molecules Article The soft coral genus Sinularia is a rich source of bioactive metabolites containing a diverse array of chemical structures. A solvent extract of Sinularia polydactyla resulted in the isolation of three new casbane diterpenes: sinularcasbane M (1), sinularcasbane N (2) and sinularcasbane O (3); in addition, known metabolites (4–5) were isolated. Compounds were elucidated on the basis of spectroscopic analyses; the absolute configuration was confirmed by X-ray analysis. MDPI 2016-03-03 /pmc/articles/PMC6274415/ /pubmed/26950110 http://dx.doi.org/10.3390/molecules21030308 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hegazy, Mohamed-Elamir F.
Mohamed, Tarik A.
Elshamy, Abdelsamed I.
Al-Hammady, Montaser A.
Ohta, Shinji
Paré, Paul W.
Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title_full Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title_fullStr Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title_full_unstemmed Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title_short Casbane Diterpenes from Red Sea Coral Sinularia polydactyla
title_sort casbane diterpenes from red sea coral sinularia polydactyla
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274415/
https://www.ncbi.nlm.nih.gov/pubmed/26950110
http://dx.doi.org/10.3390/molecules21030308
work_keys_str_mv AT hegazymohamedelamirf casbanediterpenesfromredseacoralsinulariapolydactyla
AT mohamedtarika casbanediterpenesfromredseacoralsinulariapolydactyla
AT elshamyabdelsamedi casbanediterpenesfromredseacoralsinulariapolydactyla
AT alhammadymontasera casbanediterpenesfromredseacoralsinulariapolydactyla
AT ohtashinji casbanediterpenesfromredseacoralsinulariapolydactyla
AT parepaulw casbanediterpenesfromredseacoralsinulariapolydactyla