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Total Synthesis of Chiral Falcarindiol Analogues Using BINOL-Promoted Alkyne Addition to Aldehydes

An enantioselective total synthesis of chiral falcarindiol analogues from buta-1,3-diyn-1-yltriisopropylsilane is reported. The key step in this synthesis is BINOL-promoted asymmetric diacetylene addition to aldehydes. The two chiral centers of the falcarindiol analogues can be produced by using the...

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Detalles Bibliográficos
Autores principales:	Wang, Li, Shou, Ping-Ping, Wei, Si-Ping, Zhang, Chun, Li, Shuang-Xun, Liu, Ping-Xian, Du, Xi, Wang, Qin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274458/ https://www.ncbi.nlm.nih.gov/pubmed/26797597 http://dx.doi.org/10.3390/molecules21010112

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