Synthesis and Cytotoxic Activity on Human Cancer Cells of Novel Isoquinolinequinone–Amino Acid Derivatives

A variety of aminoisoquinoline-5,8-quinones bearing α-amino acids moieties were synthesized from 3-methyl-4-methoxycarbonylisoquinoline-5,8-quinone and diverse l- and d-α-amino acid methyl esters. The members of the series were evaluated for their cytotoxic activity against normal and cancer cell li...

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Detalles Bibliográficos
Autores principales: Valderrama, Jaime A., Delgado, Virginia, Sepúlveda, Sandra, Benites, Julio, Theoduloz, Cristina, Buc Calderon, Pedro, Muccioli, Giulio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274474/
https://www.ncbi.nlm.nih.gov/pubmed/27617997
http://dx.doi.org/10.3390/molecules21091199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274474/
https://www.ncbi.nlm.nih.gov/pubmed/27617997
http://dx.doi.org/10.3390/molecules21091199

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