Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans

A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.

Detalles Bibliográficos
Autores principales: Lin, Mei-Huey, Chen, Yu-Chun, Chiu, Shih-Hao, Chen, Yun-Fan, Chuang, Tsung-Hsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274509/
https://www.ncbi.nlm.nih.gov/pubmed/28009840
http://dx.doi.org/10.3390/molecules21121713
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author Lin, Mei-Huey
Chen, Yu-Chun
Chiu, Shih-Hao
Chen, Yun-Fan
Chuang, Tsung-Hsun
author_facet Lin, Mei-Huey
Chen, Yu-Chun
Chiu, Shih-Hao
Chen, Yun-Fan
Chuang, Tsung-Hsun
author_sort Lin, Mei-Huey
collection PubMed
description A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets.
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spelling pubmed-62745092018-12-28 Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans Lin, Mei-Huey Chen, Yu-Chun Chiu, Shih-Hao Chen, Yun-Fan Chuang, Tsung-Hsun Molecules Article A new strategy for cyclopenta[b]furan synthesis mediated by hypervalent iodine(III) has been described. The approach employs diacetoxyiodobenzene-induced initial dehydrogenation to a putative trienone intermediate and triggered sequential cycloisomerization to form the cyclo-penta[b]furan targets. MDPI 2016-12-21 /pmc/articles/PMC6274509/ /pubmed/28009840 http://dx.doi.org/10.3390/molecules21121713 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lin, Mei-Huey
Chen, Yu-Chun
Chiu, Shih-Hao
Chen, Yun-Fan
Chuang, Tsung-Hsun
Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title_full Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title_fullStr Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title_full_unstemmed Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title_short Hypervalent Iodine(III)-Induced Domino Oxidative Cyclization for the Synthesis of Cyclopenta[b]furans
title_sort hypervalent iodine(iii)-induced domino oxidative cyclization for the synthesis of cyclopenta[b]furans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274509/
https://www.ncbi.nlm.nih.gov/pubmed/28009840
http://dx.doi.org/10.3390/molecules21121713
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