Validation and Application of an Ultra High-Performance Liquid Chromatography Tandem Mass Spectrometry Method for Yuanhuacine Determination in Rat Plasma after Pulmonary Administration: Pharmacokinetic Evaluation of a New Drug Delivery System

Yuanhuacine was found to have significant inhibitory activity against A-549 human lung cancer cells. However, there would be serious adverse toxicity effects after systemic administration of yuanhuacine, such as by oral and intravenous ways. In order to achieve better curative effect and to alleviat...

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Detalles Bibliográficos
Autores principales: Li, Man, Liu, Xiao, Cai, Hao, Shen, Zhichun, Xu, Liu, Li, Weidong, Wu, Li, Duan, Jinao, Chen, Zhipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274523/
https://www.ncbi.nlm.nih.gov/pubmed/27999290
http://dx.doi.org/10.3390/molecules21121733

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