Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis

Chiral pool α-amino acids have been used as powerful tools for the total synthesis of structurally diverse natural products. Some common naturally occurring α-amino acids are readily available in both enantiomerically pure forms. The applications of the chiral pool in asymmetric synthesis can be cat...

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Detalles Bibliográficos
Autores principales: Paek, Seung-Mann, Jeong, Myeonggyo, Jo, Jeyun, Heo, Yu Mi, Han, Young Taek, Yun, Hwayoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274556/
https://www.ncbi.nlm.nih.gov/pubmed/27455209
http://dx.doi.org/10.3390/molecules21070951
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author Paek, Seung-Mann
Jeong, Myeonggyo
Jo, Jeyun
Heo, Yu Mi
Han, Young Taek
Yun, Hwayoung
author_facet Paek, Seung-Mann
Jeong, Myeonggyo
Jo, Jeyun
Heo, Yu Mi
Han, Young Taek
Yun, Hwayoung
author_sort Paek, Seung-Mann
collection PubMed
description Chiral pool α-amino acids have been used as powerful tools for the total synthesis of structurally diverse natural products. Some common naturally occurring α-amino acids are readily available in both enantiomerically pure forms. The applications of the chiral pool in asymmetric synthesis can be categorized prudently as chiral sources, devices, and inducers. This review specifically examines recent advances in substrate-controlled asymmetric reactions induced by the chirality of α-amino acid templates in natural product synthesis research and related areas.
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spelling pubmed-62745562018-12-28 Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis Paek, Seung-Mann Jeong, Myeonggyo Jo, Jeyun Heo, Yu Mi Han, Young Taek Yun, Hwayoung Molecules Review Chiral pool α-amino acids have been used as powerful tools for the total synthesis of structurally diverse natural products. Some common naturally occurring α-amino acids are readily available in both enantiomerically pure forms. The applications of the chiral pool in asymmetric synthesis can be categorized prudently as chiral sources, devices, and inducers. This review specifically examines recent advances in substrate-controlled asymmetric reactions induced by the chirality of α-amino acid templates in natural product synthesis research and related areas. MDPI 2016-07-21 /pmc/articles/PMC6274556/ /pubmed/27455209 http://dx.doi.org/10.3390/molecules21070951 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Paek, Seung-Mann
Jeong, Myeonggyo
Jo, Jeyun
Heo, Yu Mi
Han, Young Taek
Yun, Hwayoung
Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title_full Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title_fullStr Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title_full_unstemmed Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title_short Recent Advances in Substrate-Controlled Asymmetric Induction Derived from Chiral Pool α-Amino Acids for Natural Product Synthesis
title_sort recent advances in substrate-controlled asymmetric induction derived from chiral pool α-amino acids for natural product synthesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274556/
https://www.ncbi.nlm.nih.gov/pubmed/27455209
http://dx.doi.org/10.3390/molecules21070951
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