Cargando…
The adult human testis transcriptional cell atlas
Human adult spermatogenesis balances spermatogonial stem cell (SSC) self-renewal and differentiation, alongside complex germ cell-niche interactions, to ensure long-term fertility and faithful genome propagation. Here, we performed single-cell RNA sequencing of ~6500 testicular cells from young adul...
Autores principales: | Guo, Jingtao, Grow, Edward J., Mlcochova, Hana, Maher, Geoffrey J., Lindskog, Cecilia, Nie, Xichen, Guo, Yixuan, Takei, Yodai, Yun, Jina, Cai, Long, Kim, Robin, Carrell, Douglas T., Goriely, Anne, Hotaling, James M., Cairns, Bradley R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274646/ https://www.ncbi.nlm.nih.gov/pubmed/30315278 http://dx.doi.org/10.1038/s41422-018-0099-2 |
Ejemplares similares
-
The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty
por: Guo, Jingtao, et al.
Publicado: (2020) -
Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human Spermatogonial Stem Cell Development
por: Guo, Jingtao, et al.
Publicado: (2017) -
Dissecting mammalian spermatogenesis using spatial transcriptomics
por: Chen, Haiqi, et al.
Publicado: (2021) -
Using sperm testing to improve patient and offspring health: rational, evidence-based care of the infertile male in the ART clinic
por: Carrell, Douglas T., et al.
Publicado: (2017) -
Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer
por: Tharmalingam, Melissa D., et al.
Publicado: (2020)