Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease—Activated Receptor-2, in Human Corneal Epithelial Cells

Cathepsin S (CTSS) activity is increased in tears of Sjögren’s syndrome (SS) patients. This elevated CTSS may contribute to ocular surface inflammation. Human corneal epithelial cells (HCE-T cells) were treated with recombinant human CTSS at activity comparable to that in SS patient tears for 2, 4,...

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Detalles Bibliográficos
Autores principales: Klinngam, Wannita, Fu, Runzhong, Janga, Srikanth R., Edman, Maria C., Hamm-Alvarez, Sarah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274678/
https://www.ncbi.nlm.nih.gov/pubmed/30423938
http://dx.doi.org/10.3390/ijms19113530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274678/
https://www.ncbi.nlm.nih.gov/pubmed/30423938
http://dx.doi.org/10.3390/ijms19113530

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