Deciphering Molecular and Phenotypic Changes Associated with Early Autoimmune Disease in the Aire-Deficient Mouse Model of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely unknown, and studies historically focus on defining late-stage disease...

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Detalles Bibliográficos
Autores principales: Chen, Feeling YuTing, Gaylord, Eliza, McNamara, Nancy, Knox, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274681/
https://www.ncbi.nlm.nih.gov/pubmed/30453645
http://dx.doi.org/10.3390/ijms19113628

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