Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells

Background: Several mechanisms of action have been proposed to explain the apparent antineoplastic functions of metformin, many of which are observed at high concentrations that may not be reflective of achievable tissue concentrations. We propose that metformin at low concentrations functions to in...

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Detalles Bibliográficos
Autores principales: Schexnayder, Chandler, Broussard, Kiera, Onuaguluchi, Demitrius, Poché, Anthony, Ismail, Moamen, McAtee, LeFontae, Llopis, Shawn, Keizerweerd, Amber, McFerrin, Harris, Williams, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274682/
https://www.ncbi.nlm.nih.gov/pubmed/30469399
http://dx.doi.org/10.3390/ijms19113692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274682/
https://www.ncbi.nlm.nih.gov/pubmed/30469399
http://dx.doi.org/10.3390/ijms19113692

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