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Biotherapeutics: Challenges and Opportunities for Predictive Toxicology of Monoclonal Antibodies
Biotherapeutics are a rapidly growing portion of the total pharmaceutical market accounting for almost one-half of recent new drug approvals. A major portion of these approvals each year are monoclonal antibodies (mAbs). During development, non-clinical pharmacology and toxicology testing of mAbs di...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274697/ https://www.ncbi.nlm.nih.gov/pubmed/30469350 http://dx.doi.org/10.3390/ijms19113685 |