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HGF/c-MET: A Promising Therapeutic Target in the Digestive System Cancers

The HGF/c-MET pathway is active in the development of digestive system cancers, indicating that inhibition of HGF/c-MET signaling may have therapeutic potential. Various HGF/c-MET signaling inhibitors, mainly c-MET inhibitors, have been tested in clinical trials. The observed efficacy and adverse ev...

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Detalles Bibliográficos
Autores principales: Zhang, Hongli, Feng, Qingqing, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274736/
https://www.ncbi.nlm.nih.gov/pubmed/30360560
http://dx.doi.org/10.3390/ijms19113295