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Causal Transcription Regulatory Network Inference Using Enhancer Activity as a Causal Anchor

Transcription control plays a crucial role in establishing a unique gene expression signature for each of the hundreds of mammalian cell types. Though gene expression data have been widely used to infer cellular regulatory networks, existing methods mainly infer correlations rather than causality. W...

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Detalles Bibliográficos
Autores principales: Vipin, Deepti, Wang, Lingfei, Devailly, Guillaume, Michoel, Tom, Joshi, Anagha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274755/
https://www.ncbi.nlm.nih.gov/pubmed/30445760
http://dx.doi.org/10.3390/ijms19113609