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Intravenous Delivery of piggyBac Transposons as a Useful Tool for Liver-Specific Gene-Switching
Hydrodynamics-based gene delivery (HGD) is an efficient method for transfecting plasmid DNA into hepatocytes in vivo. However, the resulting gene expression is transient, and occurs in a non-tissue specific manner. The piggyBac (PB) transposon system allows chromosomal integration of a transgene in...
Autores principales: | Nakamura, Shingo, Ishihara, Masayuki, Watanabe, Satoshi, Ando, Naoko, Ohtsuka, Masato, Sato, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274756/ https://www.ncbi.nlm.nih.gov/pubmed/30400245 http://dx.doi.org/10.3390/ijms19113452 |
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