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Topical Administration of Bosentan Prevents Retinal Neurodegeneration in Experimental Diabetes

Experimental evidence suggests that endothelin 1 (ET-1) is involved in the development of retinal microvascular abnormalities induced by diabetes. The effects of ET-1 are mediated by endothelin A- and B-receptors (ETA and ETB). Endothelin B-receptors activation mediates retinal neurodegeneration but...

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Detalles Bibliográficos
Autores principales:	Bogdanov, Patricia, Simó-Servat, Olga, Sampedro, Joel, Solà-Adell, Cristina, Garcia-Ramírez, Marta, Ramos, Hugo, Guerrero, Marta, Suñé-Negre, Josep Maria, Ticó, Josep Ramon, Montoro, Bruno, Durán, Vicente, Arias, Luís, Hernández, Cristina, Simó, Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274769/ https://www.ncbi.nlm.nih.gov/pubmed/30428543 http://dx.doi.org/10.3390/ijms19113578

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