Cargando…

Inhibition of Microglia-Derived Oxidative Stress by Ciliary Neurotrophic Factor Protects Dopamine Neurons In Vivo from MPP(+) Neurotoxicity

We demonstrated that capsaicin (CAP), an agonist of transient receptor potential vanilloid subtype 1 (TRPV1), inhibits microglia activation and microglia-derived oxidative stress in the substantia nigra (SN) of MPP(+)-lesioned rat. However, the detailed mechanisms how microglia-derived oxidative str...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baek, Jeong Yeob, Jeong, Jae Yeong, Kim, Kyoung In, Won, So-Yoon, Chung, Young Cheul, Nam, Jin Han, Cho, Eun Ju, Ahn, Tae-Beom, Bok, Eugene, Shin, Won-Ho, Jin, Byung Kwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274815/ https://www.ncbi.nlm.nih.gov/pubmed/30423807 http://dx.doi.org/10.3390/ijms19113543

Ejemplares similares

Delayed Treatment of Capsaicin Produces Partial Motor Recovery by Enhancing Dopamine Function in MPP(+)-lesioned Rats via Ciliary Neurotrophic Factor
por: Kim, Kyoung In, et al.
Publicado: (2019)

Interleukin 13 on Microglia is Neurotoxic in Lipopolysaccharide-injected Striatum in vivo
por: Hong, Ah Reum, et al.
Publicado: (2022)

Interleukin-4 and Interleukin-13 Exacerbate Neurotoxicity of Prothrombin Kringle-2 in Cortex In Vivo via Oxidative Stress
por: Jeong, Jae Yeong, et al.
Publicado: (2019)

Microglia-dependent neuroprotective effects of 4-octyl itaconate against rotenone-and MPP+-induced neurotoxicity in Parkinson’s disease
por: Xia, Ning, et al.
Publicado: (2023)

Interleukin-13 Propagates Prothrombin Kringle-2-Induced Neurotoxicity in Hippocampi In Vivo via Oxidative Stress
por: Jeong, Jae Yeong, et al.
Publicado: (2021)

Bacopa Protects against Neurotoxicity Induced by MPP(+) and Methamphetamine
por: Ferrucci, Michela, et al.
Publicado: (2022)

In vitro neuroprotective effects of ciliary neurotrophic factor on dorsal root ganglion neurons with glutamate-induced neurotoxicity
por: Wen, Shu-yun, et al.
Publicado: (2017)

Norfluoxetine Prevents Degeneration of Dopamine Neurons by Inhibiting Microglia-Derived Oxidative Stress in an MPTP Mouse Model of Parkinson's Disease
por: Kim, Kyung In, et al.
Publicado: (2018)

Capsaicin prevents degeneration of dopamine neurons by inhibiting glial activation and oxidative stress in the MPTP model of Parkinson's disease
por: Chung, Young C, et al.
Publicado: (2017)

Wld(S )but not Nmnat1 protects dopaminergic neurites from MPP(+ )neurotoxicity
por: Antenor-Dorsey, Jo Ann V, et al.
Publicado: (2012)

Resveratrol Induces the Expression of Interleukin-10 and Brain-Derived Neurotrophic Factor in BV2 Microglia under Hypoxia
por: Song, Juhyun, et al.
Publicado: (2014)

CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson's disease
por: Chung, Young C, et al.
Publicado: (2016)

Paeonolum protects against MPP(+)-induced neurotoxicity in zebrafish and PC12 cells
por: Lu, Xi-Lin, et al.
Publicado: (2015)

Carnitine Protects against MPP(+)-Induced Neurotoxicity and Inflammation by Promoting Primary Ciliogenesis in SH-SY5Y Cells
por: Bae, Ji-Eun, et al.
Publicado: (2022)

Roles of Autophagy in MPP(+)-Induced Neurotoxicity In Vivo: The Involvement of Mitochondria and α-Synuclein Aggregation
por: Hung, Kai-Chih, et al.
Publicado: (2014)

Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
por: Bok, Eugene, et al.
Publicado: (2018)

Inhibitory effects of curcumin and cyclocurcumin in 1-methyl-4-phenylpyridinium (MPP(+)) induced neurotoxicity in differentiated PC12 cells
por: Chakraborty, Sandeep, et al.
Publicado: (2017)

Methamphetamine neurotoxicity, microglia, and neuroinflammation
por: Shaerzadeh, Fatemeh, et al.
Publicado: (2018)

Valproic Acid Protects Primary Dopamine Neurons from MPP(+)-Induced Neurotoxicity: Involvement of GSK3β Phosphorylation by Akt and ERK through the Mitochondrial Intrinsic Apoptotic Pathway
por: Zhang, Chi, et al.
Publicado: (2017)

MPP(+)-induced toxicity in the presence of dopamine is mediated by COX-2 through oxidative stress
por: Hsieh, Ya-Ching, et al.
Publicado: (2011)

Biological Effects of Ciliary Neurotrophic Factor on hMADS Adipocytes
por: Perugini, Jessica, et al.
Publicado: (2019)

Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas
por: Do Rhee, Kun, et al.
Publicado: (2022)

Sulfuretin Attenuates MPP(+)-Induced Neurotoxicity through Akt/GSK3β and ERK Signaling Pathways
por: Pariyar, Ramesh, et al.
Publicado: (2017)

The Alteration of Nasopharyngeal and Oropharyngeal Microbiota in Children with MPP and Non-MPP
por: Lu, Zhiwei, et al.
Publicado: (2017)

Echinacoside protects against MPTP/MPP(+)-induced neurotoxicity via regulating autophagy pathway mediated by Sirt1
por: Chen, Chang, et al.
Publicado: (2018)

miR‐30b protects nigrostriatal dopaminergic neurons from MPP(+)‐induced neurotoxicity via SNCA
por: Shen, Yu‐fei, et al.
Publicado: (2020)

Expression of ciliary neurotrophic factor and its receptor in experimental obstructive nephropathy
por: Lee, Byoung-Seung, et al.
Publicado: (2011)

The trophic effect of ciliary neurotrophic factor on injured masseter muscle in rat
por: Zhang, Yujun, et al.
Publicado: (2015)

Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex
por: Senzacqua, Martina, et al.
Publicado: (2016)

Modulation of matrix metalloproteases by ciliary neurotrophic factor in human placental development
por: Tossetta, Giovanni, et al.
Publicado: (2022)

Differential Roles of Tubby Family Proteins in Ciliary Formation and Trafficking
por: Hong, Julie J., et al.
Publicado: (2021)

Effects of Apamin on MPP(+)-Induced Calcium Overload and Neurotoxicity by Targeting CaMKII/ERK/p65/STAT3 Signaling Pathways in Dopaminergic Neuronal Cells
por: Park, Jihyun, et al.
Publicado: (2022)

Ciliary Neurotrophic Factor Derived From Astrocytes Protects Retinal Ganglion Cells Through PI3K/AKT, JAK/STAT, and MAPK/ERK Pathways
por: Lee, Kwanghyun, et al.
Publicado: (2022)

2013 MPP Workshop
por: Jonker, Michael
Publicado: (2014)

Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway
por: Guo, Xingfang, et al.
Publicado: (2019)

Polygonatum sibiricum Polysaccharides Protect against MPP-Induced Neurotoxicity via the Akt/mTOR and Nrf2 Pathways
por: Huang, Si, et al.
Publicado: (2021)

Ramelteon ameliorated 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in neuronal cells in a mitochondrial-dependent pathway
por: Li, Chuo, et al.
Publicado: (2021)

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
por: Yang, Xiaoxia, et al.
Publicado: (2018)

Interleukin-4-Mediated Oxidative Stress Is Harmful to Hippocampal Neurons of Prothrombin Kringle-2-Lesioned Rat In Vivo
por: Chung, Young Cheul, et al.
Publicado: (2020)

Ciliary neurotrophic factor induces cholinergic differentiation of rat sympathetic neurons in culture
Publicado: (1989)

Cannot write session to /tmp/vufind_sessions/sess_i21vrvaffamiktam7hgkucfm10