Cargando…

Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia

Background: In Acute Myeloid Leukemia (AML), a complete response to chemotherapy is usually obtained after conventional chemotherapy but overall patient survival is poor due to highly frequent relapses. As opposed to chronic myeloid leukemia, B lymphoma or multiple myeloma, AML is one of the rare ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stuani, Lucille, Riols, Fabien, Millard, Pierre, Sabatier, Marie, Batut, Aurélie, Saland, Estelle, Viars, Fanny, Tonini, Laure, Zaghdoudi, Sonia, Linares, Laetitia K., Portais, Jean-Charles, Sarry, Jean-Emmanuel, Bertrand-Michel, Justine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274868/ https://www.ncbi.nlm.nih.gov/pubmed/30366412 http://dx.doi.org/10.3390/ijms19113325

Ejemplares similares

Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia
por: Stuani, Lucille, et al.
Publicado: (2019)

Impact of kinetic isotope effects in isotopic studies of metabolic systems
por: Millard, Pierre, et al.
Publicado: (2015)

Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
por: Boutzen, Héléna, et al.
Publicado: (2016)

Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations
por: Sabatier, Marie, et al.
Publicado: (2021)

Improving lipid mapping in Genome Scale Metabolic Networks using ontologies
por: Poupin, Nathalie, et al.
Publicado: (2020)

Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells
por: Larrue, Clément, et al.
Publicado: (2021)

Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway
por: Enjalbert, Brice, et al.
Publicado: (2017)

Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia
por: Larrue, Clément, et al.
Publicado: (2019)

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
por: Bosc, Claudie, et al.
Publicado: (2020)

An optimization method for untargeted MS-based isotopic tracing investigations of metabolism
por: Butin, Noémie, et al.
Publicado: (2022)

CD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia
por: Farge, Thomas, et al.
Publicado: (2023)

Control and regulation of acetate overflow in Escherichia coli
por: Millard, Pierre, et al.
Publicado: (2021)

Dexamethasone in hyperleukocytic acute myeloid leukemia
por: Bertoli, Sarah, et al.
Publicado: (2018)

The Carbon Storage Regulator (Csr) System Exerts a Nutrient-Specific Control over Central Metabolism in Escherichia coli Strain Nissle 1917
por: Revelles, Olga, et al.
Publicado: (2013)

Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo
por: Serhan, Nizar, et al.
Publicado: (2020)

SHED-Dependent Oncogenic Signaling of the PEAK3 Pseudo-Kinase
por: Ounoughene, Youcef, et al.
Publicado: (2021)

Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
por: Stuani, Lucille, et al.
Publicado: (2021)

Phenotypically-defined stages of leukemia arrest predict main driver mutations subgroups, and outcome in acute myeloid leukemia
por: Vergez, François, et al.
Publicado: (2022)

Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia
por: Mouchel, Pierre-Luc, et al.
Publicado: (2020)

Intuitive Visualization and Analysis of Multi-Omics Data and Application to Escherichia coli Carbon Metabolism
por: Enjalbert, Brice, et al.
Publicado: (2011)

Physiological and Molecular Timing of the Glucose to Acetate Transition in Escherichia coli
por: Enjalbert, Brice, et al.
Publicado: (2013)

Recent highlights in biosynthesis research using stable isotopes
por: Rinkel, Jan, et al.
Publicado: (2015)

ScalaFlux: A scalable approach to quantify fluxes in metabolic subnetworks
por: Millard, Pierre, et al.
Publicado: (2020)

Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
por: Sesen, Julie, et al.
Publicado: (2015)

Sequential Isotopic Signature Along Gladius Highlights Contrasted Individual Foraging Strategies of Jumbo Squid (Dosidicus gigas)
por: Lorrain, Anne, et al.
Publicado: (2011)

Developmental stage-dependent metabolic regulation during meiotic differentiation in budding yeast
por: Walther, Thomas, et al.
Publicado: (2014)

Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2(V617F) myeloproliferative neoplasms
por: Courdy, Charly, et al.
Publicado: (2023)

Functional analysis of isoprenoid precursors biosynthesis by quantitative metabolomics and isotopologue profiling
por: Castaño-Cerezo, Sara, et al.
Publicado: (2019)

Theoretical Basis for Dynamic Label Propagation in Stationary Metabolic Networks under Step and Periodic Inputs
por: Sokol, Serguei, et al.
Publicado: (2015)

CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia
por: Bertoli, Sarah, et al.
Publicado: (2015)

Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold
por: Griessinger, Emmanuel, et al.
Publicado: (2023)

Control of ATP homeostasis during the respiro-fermentative transition in yeast
por: Walther, Thomas, et al.
Publicado: (2010)

Structure and Function of the LmbE-like Superfamily
por: Viars, Shane, et al.
Publicado: (2014)

Oncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid leukemia
por: Heydt, Q, et al.
Publicado: (2018)

Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli
por: Létoffé, Sylvie, et al.
Publicado: (2017)

Effects of Dietary Eicosapentaenoic Acid (EPA) Supplementation in High-Fat Fed Mice on Lipid Metabolism and Apelin/APJ System in Skeletal Muscle
por: Bertrand, Chantal, et al.
Publicado: (2013)

Comparative Time-Scale Gene Expression Analysis Highlights the Infection Processes of Two Amoebophrya Strains
por: Farhat, Sarah, et al.
Publicado: (2018)

The interrelationship between DRIM gene expression and cytogenetic and phenotypic characteristics in human breast tumor cell lines
por: Goodison, Steve, et al.
Publicado: (2003)

Multi-isotope evidence of population aggregation in the Natufian and scant migration during the early Neolithic of the Southern Levant
por: Santana, Jonathan, et al.
Publicado: (2021)

Isotope ratio-based quantification of carbon assimilation highlights the role of plastidial isoprenoid precursor availability in photosynthesis
por: Bergman, Matthew E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vmieobej34a00ja6n7inghk4cp