NVP-BEZ235 Attenuated Cell Proliferation and Migration in the Squamous Cell Carcinoma of Oral Cavities and p70S6K Inhibition Mimics its Effect

NVP-BEZ235 or BEZ235 is a dual inhibitor of adenosine triphosphate (ATP)-competitive phosphoinositide 3-kinase (PI3K)/mammalian-target-of-rapamycin (mTOR) and is promising for cancer treatment. Because it targets more than one downstream effector, a dual approach is promising for cancer treatment. T...

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Detalles Bibliográficos
Autores principales: Hsu, Cheng-Ming, Lin, Pai-Mei, Lin, Hsin-Ching, Tsai, Yao-Te, Tsai, Ming-Shao, Li, Shau-Hsuan, Wu, Ching-Yuan, Yang, Yao-Hsu, Lin, Sheng-Fung, Yang, Ming-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274880/
https://www.ncbi.nlm.nih.gov/pubmed/30423811
http://dx.doi.org/10.3390/ijms19113546

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