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Administration of Downstream ApoE Attenuates the Adverse Effect of Brain ABCA1 Deficiency on Stroke
The ATP-binding cassette transporter member A1 (ABCA1) and apolipoprotein E (ApoE) are major cholesterol transporters that play important roles in cholesterol homeostasis in the brain. Previous research demonstrated that specific deletion of brain-ABCA1 (ABCA1(−B/−B)) reduced brain grey matter (GM)...
Autores principales: | Wang, Xiaohui, Li, Rongwen, Zacharek, Alex, Landschoot-Ward, Julie, Wang, Fengjie, Wu, Kuan-Han Hank, Chopp, Michael, Chen, Jieli, Cui, Xu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274914/ https://www.ncbi.nlm.nih.gov/pubmed/30373276 http://dx.doi.org/10.3390/ijms19113368 |
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