The Potential Role of a Soluble γ-Chain Cytokine Receptor as a Regulator of IL-7-Induced Lymphoproliferative Disorders

IL-7 is an essential, nonredundant growth factor for T and B cell generation and maintenance. While IL-7 deficiency results in lymphopenia, overexpression of IL-7 can cause neoplasia in experimental models. IL-7’s involvement in neoplasia has been appreciated through studies of IL-7 transgenic (Tg)...

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Detalles Bibliográficos
Autores principales: Kim, Geona, Jo, Yuna, Lee, Byunghyuk, Ali, Laraib Amir, Lee, Boae, Hong, Changwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274946/
https://www.ncbi.nlm.nih.gov/pubmed/30373315
http://dx.doi.org/10.3390/ijms19113375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274946/
https://www.ncbi.nlm.nih.gov/pubmed/30373315
http://dx.doi.org/10.3390/ijms19113375

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