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Hypoxic Microenvironment and Metastatic Bone Disease
Hypoxia is a common feature of solid tumors and is associated with an increased risk of metastasis and a poor prognosis. Recent imaging techniques revealed that bone marrow contains a quite hypoxic microenvironment. Low oxygen levels activate hypoxia signaling pathways such as hypoxia-inducible fact...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274963/ https://www.ncbi.nlm.nih.gov/pubmed/30423905 http://dx.doi.org/10.3390/ijms19113523 |