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Repression of Transcriptional Activity of Forkhead Box O1 by Histone Deacetylase Inhibitors Ameliorates Hyperglycemia in Type 2 Diabetic Rats

Type 2 diabetes mellitus (T2DM) is a chronic disease manifested by hyperglycemia. It is essential to effectively control hyperglycemia to prevent complications of T2DM. Here, we hypothesize that repression of transcriptional activity of forkhead box O1 (FoxO1) via histone deacetylase inhibitors (HDA...

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Detalles Bibliográficos
Autores principales: Cho, Hyun Min, Seok, Young Mi, Lee, Hae Ahm, Song, Minji, Kim, InKyeom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274985/
https://www.ncbi.nlm.nih.gov/pubmed/30424007
http://dx.doi.org/10.3390/ijms19113539