Cargando…
Adipose Stem Cell Translational Applications: From Bench-to-Bedside
During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275042/ https://www.ncbi.nlm.nih.gov/pubmed/30400641 http://dx.doi.org/10.3390/ijms19113475 |
_version_ | 1783377748706721792 |
---|---|
author | Argentati, Chiara Morena, Francesco Bazzucchi, Martina Armentano, Ilaria Emiliani, Carla Martino, Sabata |
author_facet | Argentati, Chiara Morena, Francesco Bazzucchi, Martina Armentano, Ilaria Emiliani, Carla Martino, Sabata |
author_sort | Argentati, Chiara |
collection | PubMed |
description | During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons for this success. Here, we document the advances in the biology and in the innovative biotechnological applications of ASCs. We discuss how the multipotential property boosts ASCs toward mesenchymal and non-mesenchymal differentiation cell lineages and how their character is maintained even if they are combined with gene delivery systems and/or biomaterials, both in vitro and in vivo. |
format | Online Article Text |
id | pubmed-6275042 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62750422018-12-15 Adipose Stem Cell Translational Applications: From Bench-to-Bedside Argentati, Chiara Morena, Francesco Bazzucchi, Martina Armentano, Ilaria Emiliani, Carla Martino, Sabata Int J Mol Sci Review During the last five years, there has been a significantly increasing interest in adult adipose stem cells (ASCs) as a suitable tool for translational medicine applications. The abundant and renewable source of ASCs and the relatively simple procedure for cell isolation are only some of the reasons for this success. Here, we document the advances in the biology and in the innovative biotechnological applications of ASCs. We discuss how the multipotential property boosts ASCs toward mesenchymal and non-mesenchymal differentiation cell lineages and how their character is maintained even if they are combined with gene delivery systems and/or biomaterials, both in vitro and in vivo. MDPI 2018-11-05 /pmc/articles/PMC6275042/ /pubmed/30400641 http://dx.doi.org/10.3390/ijms19113475 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Argentati, Chiara Morena, Francesco Bazzucchi, Martina Armentano, Ilaria Emiliani, Carla Martino, Sabata Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title | Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title_full | Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title_fullStr | Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title_full_unstemmed | Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title_short | Adipose Stem Cell Translational Applications: From Bench-to-Bedside |
title_sort | adipose stem cell translational applications: from bench-to-bedside |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275042/ https://www.ncbi.nlm.nih.gov/pubmed/30400641 http://dx.doi.org/10.3390/ijms19113475 |
work_keys_str_mv | AT argentatichiara adiposestemcelltranslationalapplicationsfrombenchtobedside AT morenafrancesco adiposestemcelltranslationalapplicationsfrombenchtobedside AT bazzucchimartina adiposestemcelltranslationalapplicationsfrombenchtobedside AT armentanoilaria adiposestemcelltranslationalapplicationsfrombenchtobedside AT emilianicarla adiposestemcelltranslationalapplicationsfrombenchtobedside AT martinosabata adiposestemcelltranslationalapplicationsfrombenchtobedside |