ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning

MOTIVATION: The identification of functional sequence variations in regulatory DNA regions is one of the major challenges of modern genetics. Here, we report results of a combined multifactor analysis of properties characterizing functional sequence variants located in promoter regions of genes. RES...

Descripción completa

Detalles Bibliográficos
Autores principales: Malkowska, Maja, Zubek, Julian, Plewczynski, Dariusz, Wyrwicz, Lucjan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275119/
https://www.ncbi.nlm.nih.gov/pubmed/30519505
http://dx.doi.org/10.7717/peerj.5742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275119/
https://www.ncbi.nlm.nih.gov/pubmed/30519505
http://dx.doi.org/10.7717/peerj.5742

Ejemplares similares